Even before Stephen King's 11/22/63 had been released, Jonathan Demme (The Silence of the Lambs) had acquired film rights, with plans to write and direct. We haven't heard much on the project since last year and it has been revealed that Demme is no longer working on the adaptation.

The Playlist recently spoke with Demme, who told them that the reason behind him exiting the project was that he and Stephen King had different ideas for what they wanted to see in the script:

"This is a big book, with lots in it. And I loved certain parts of the book for the film more than Stephen did. We're friends, and I had a lot of fun working on the script, but we were too apart on what we felt should be in and what should be out of the script... I had an option and I let it go. But I hope it's moving forward, I really want to see that movie."

11/22/63 was released on November 8th, 2011 and is a time travel tale that revolves around the assassination of JFK:

“Jake Epping is a thirty-five-year-old high school English teacher in Lisbon Falls, Maine, who makes extra money teaching adults in the GED program. He receives an essay from one of the students—a gruesome, harrowing first person story about the night 50 years ago when Harry Dunning’s father came home and killed his mother, his sister, and his brother with a hammer. Harry escaped with a smashed leg, as evidenced by his crooked walk.

Not much later, Jake’s friend Al, who runs the local diner, divulges a secret: his storeroom is a portal to 1958. He enlists Jake on an insane—and insanely possible—mission to try to prevent the Kennedy assassination. So begins Jake’s new life as George Amberson and his new world of Elvis and JFK, of big American cars and sock hops, of a troubled loner named Lee Harvey Oswald and a beautiful high school librarian named Sadie Dunhill, who becomes the love of Jake’s life—a life that transgresses all the normal rules of time.”

Source: The Playlist