After the success of Dead Space 2, the development of a third game was pretty much a given. However, we weren't sure what direction the game would be taking and supposedly leaked plot details from Dead Space 3 suggest that the game isn't just going to be "more of the same".
According to a report on Siliconera, Dead Space 3 will take place on the ice planet Tau Volantis:
"Early in Dead Space 3, Isaac crash lands on the planet. He believes he may be the only survivor and makes his way to an abandoned waystation, which he uses for shelter from the snowstorm. There he finds a survivor who is severely injured. Isaac speaks to the near dead comrade who reveals there are other survivors that trekked off to another facility. One of them is Ellie, a key character from the original Dead Space game. Isaac grabs a snowsuit and heads into the blizzard."
They claim that the enemies in this game are referred to as "the hive mind" and that most of the game will involve Isaac trying to survive in blizzard conditions. With the first 2 games being a good mix of Alien and The Thing, it isn't too much of a stretch for them to take this to an ice planet and could prevent the series from getting stale. Of course, this is just a rumor at this point, but we like the idea of a setting change. Most developers would opt for a quick generic sequel as a cash-in, so we don't mind them taking their time and trying something new.